New High-Resolution Imaging Technology Reveals COVID-19 Lung Pathology in Space and Time
April 1, 2021
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Using a new method called ‘high parameter imaging mass cytometry’ scientists visualize detailed cellular landscapes of the lung in infectious lung diseases at never-before-seen, single-cell resolution.
With this new technique, investigators at Weill Cornell Medicine and New York-Presbyterian target the expression of 36 proteins, to probe into the cellular composition and spatial architecture of human acute lung injury including lung tissue infected by SARS-CoV-2, the coronavirus that causes COVID-19.
Nature. The findings provide new insights into the causes of damage in these infectious lung diseases and a detailed resource for future investigations.