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and analyzes its resistance to ciprofloxacin. The test was used on penile swab samples from 66 patients in Baltimore and 151 patients in Kampala, Uganda. A compact tool performed DNA extraction, PCR, analyzed results and relayed data to patients via a phone application.
The test’s overall sensitivity was 97.7% (95% CI, 94.7%-100%), and its specificity was 97.6% (95% CI, 94.1%-100%) for
N. gonorrhoeae. Test results were also in 100% concordance with culture results for ciprofloxacin resistance.
“The advances demonstrated so far in magnetofluidic cartridge technology show great promise for delivering rapid gold-standard infectious disease diagnostics in a scalable and accessible format which could revolutionize STI treatment and rationalize antimicrobial use and stewardship,” Wang said.