Skin pigmentation mechanism confers major protection against UV-related cancers

Skin pigmentation mechanism confers major protection against UV-related cancers
A skin pigmentation mechanism that can darken the color of human skin as a natural defense against ultraviolet (UV)-associated cancers has been discovered by scientists at Massachusetts General Hospital (MGH).
Mediating the biological process is an enzyme, NNT, which plays a key role in the production of melanin (a pigment that protects the skin from harmful UV rays) and whose inhibition through a topical drug or ointment could potentially reduce the risk of skin cancers. The study was published online in
Cell.
Skin pigmentation and its regulation are critically important because pigments confer major protection against UV-related cancers of the skin, which are the most common malignancies found in humans."

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Switzerland ,Massachusetts ,United States ,David Fisher ,Elisabeth Roider ,Emily Henderson ,University Hospital Of Basel ,Cutaneous Biology Research Center ,Melanoma Center ,Harvard Medical School ,Department Of Dermatology ,Massachusetts General Hospital ,Co Corresponding Author ,University Hospital ,சுவிட்சர்லாந்து ,மாசசூசெட்ஸ் ,ஒன்றுபட்டது மாநிலங்களில் ,டேவிட் மீனவர் ,எமிலி ஹென்டர்சன் ,பல்கலைக்கழகம் மருத்துவமனை ஆஃப் பேசல் ,வெட்டு உயிரியல் ஆராய்ச்சி மையம் ,மெலனோமா மையம் ,ஹார்வர்ட் மருத்துவ பள்ளி ,துறை ஆஃப் தோல் நோய் ,மாசசூசெட்ஸ் ஜநரல் மருத்துவமனை ,பல்கலைக்கழகம் மருத்துவமனை ,