Largest evacuation in north america in decades. Fire hasnt threatened an entire city on this scale since the San Francisco earthquake 100 years ago. The fire has grown explosively since sunday. Fort mcmurray, alberta, a city of 88,000, has been evacuated. The price of oil rose worldwide because of the catastrophe in Canadas Oil Sands region. At least 90,000 people are refugees, hundreds of homes, whole neighborhoods, are gone. Ben tracy is there. Reporter parts of alberta are literally hell on earth. 49 fires are raging, at least irven burning out of control. Senior wildfire prevention manager chad morrison. Let me be clear air tankers are not going to stop this fire. This fire is an extreme fire event. I can feel the heat here. Ais is insane. Reporter after the fire tore through the town of fort mcmurray, this is what it looked like, not only burned out, but nmbed out. Theres nothing there. Theres nothing left. Eperes so many homes gone. Le reporter exhausted firefighters sprawled on the grass while a lone mountie surveyed the empty streets. Eric lavellee cant comprehend it. Its Something Like youd see out of the movies. The bank was on fire when we were driving in. The trailer park that was there is gone. The super 8 is gone. One of the gas stations is gone. Nt reporter the canadian government sent in reinforcements as huge plumes of smoke grew in the sky. No place felt safe, not even this evacuation center. There were hundreds of people in this shelter last night, but then the wind changed direction, and the fire headed this way, and they had to evacuate this evacuation center. They piled on buses in the onddle of the night and were once again forced to leave. Donna guillamot was evacuated for the second time. Its very stressful. You dont know whats burned and whats not burned. When you can go back. And now youre sitting here, and all you see is red flames. Orte pretty scary. Reporter these fires really have brought the Oil Sands Industry here in alberta to a halt, and thats because the Oil Companies have to make sure their employees are safe. But, scott, you dont hear anybody talking about the loss of business. What you hear people talking about up here is that so far there has been no loss of life directly related to these fires. Pelley lightning and drought thought to be the causes. Lin tracy near the fire line for us tonight. Ben, thank you. Well, there were no fatalities or injuries in a massive fire in houston today. A warehouse filled with hazardous chemicals went up, setting off a series of explosions. It took firefighters several ngurs to bring it under control. Today, the nations Top Republicans turned their backs on the partys presumptive nominee. Thth president s bush said they will skip the republican convention, and the speaker of the house withheld his endorsement. Major garrett on a house t vided. I think what a lot of a publicans want to see is that our ave a standard bearer that bears our standards. T reporter House Speaker paul ryan, the highest ranking g. O. P. Elected official and chair of this summers republican convention, said he neuld not endorse the presumptive nominee. Im just not ready to do that at this point. I honot there right now. Td i hope to, though, and i want to, but i think what is required is that we unify this party. And i think the bulk of the burden on unifying the party will have to come from our presumptive nominee. Or reporter ryan has previously criticized trumps inflammatory rhetoric, but said the primary process needed to play out. Le this party does not prey on eaoples prejudices. We appeal to their highest ideals. Reporter trump today did try to reach out to hispanic voters, sending this photo and tweet to mark cinco de mayo. With his nonendorsement, ryan grows a growing list of anpublican party elders who are distancing themselves from trump. Both living former g. O. P. President s george h. W. Bush and his son, george w. Bush, said they wont endorse trump or attend the partys convention. And the two previous republican mccanees, mitt romney and john mccain, will boycott the convention as well. Trump has said he can win the election even if the party does not unify behind him. But that plenty of wellknown republicans are eager to fall in line. Theyre calling now, and theyre calling us all, and theyre saying, wed love to get on the train, the trump llain, they call it, but wed love to get on the team. Ry reporter trump responded to oran by saying he wasnt ready to endorse his legislative agenda, either, though he held out hope for compromise. Haott, all year, ryan has been developing proposals and bills to help distance rank and File House Republicans from trump. Mission accomplished. Pelley major garrett, thanks. Also skeptical of donald trump, most women voters. Our cbs news poll gives Hillary Clinton a 27point lead among women, and we have more from orncy cordes. Reporter if you google clinton, the first thing that pops up is a campaign ad rffering an official hillary for america woman card for faose who sign up on line, a play off this nowinfamous trump l,mment. Well, i think the only card epe has is the womans card. A reporter clintons holding a 1ood hand, leading trump among ts. Te women, for instance by 11 points. The last democrat to win white women in a president ial election was her husband in 1996. In 2012, they went for mitt romney by 14 points. Trump insists he can make up ground because he knows what women want. Women want strong military. Hey want to know that theyre secure in our nation. Women want Womens Health issues taken care of, and hillary is not going to do it like me. Reporter as she works to cement a sisterhood, clinton has taken to accusing trump of. Demeaning women. Demeaning women. Demeaning and degrading things about women. Reporter she invoked gender politics again in a phone interview with the l. A. Times. Reporter we learned this afternoon that some of clintons top aides, including reportedly , r longtime confidant, huma abedin, have now been interviewed by the f. B. I. About clintons use of a private n rver. Clinton herself has not been interviewed yet, scott, but says ne will cooperate if asked. Pelley nancy cordes, nance, thanks very much. There hasnt been a lot of talk recently in the campaign about iraq, but that may change after e is week. Sesurprise attack killed a u. S. Navy seal tuesday in iraq. S tty officer first class Charles Keating responded to a call for help from kurdish allies and american advisers who aqre being overrun by isis. Charlie dagata is in iraq tonight. [gunfire] reporter only 20 minutes into the battle, u. S. Forces knew they were in trouble. They called for backup. gunfire then things only got worse. The navy seals rescue team found themselves pinned down in an intense firefight with over 120 isis militants. Run ov reporter kurdish soldiers and their u. S. Advisers were srced to take cover. The attack seemed to come from nowhere. And petty officer first class Charles Keating iv was among icope shot in the gun battle. Even the blackhawk helicopters that were called in to evacuate eeating came under fire. Aris launched this surprise attack at around 7 30 near the village of tel skuf. According to u. S. Officials, the militants flooded in from the south piercing the front line with three suicide truck bombs and bulldozers. Tie americans fought for nearly two hours before finally getting lsay. U. S. Officials told us the area had been relatively quiet for a month and was considered low risk. Co just shows how the front line against isis can change in a flash, scott, and how close u. S. Forces are to it. But u. S. Military officials here stress those navy seals only came forward to back up the he ficans and would not have joined the firefight otherwise. Pelley Charlie Dagata reporting from baghdad tonight. Charlie, thank you. Today, the federal government banned the sale of Electronic Cigarettes to anyone under the age of 18, and it imposed heavy olgulations on this multibilliondollar industry hrat has almost no oversight. Last year, three million k. Enagers used ecigarettes. Heres dr. Jon lapook. Reporter for years, e cigarette have been flying off the shelves, despite f. D. A. Concerns about their health sfects. With todays ruling, the agency y nally has the power to regulate them. Were finally leaving the world of the unregulated, wild, wild west when it comes to the sale of ecigarettes and cigars. Reporter mitch zeller directors the f. D. A. Center for tobacco products. More teens use ecigarettes rean regular cigarettes, and historically there was no regulation of these products whatsoever. Es reporter manufacturers of e cigarettes will be required to get their products approved by the f. D. A. And report any harmful ingredients. I finally found a smarter alternative to cigarettes. Reporter ecigarettes contain nicotine but not cancer causing tar in regular ingarettes. Both f. D. A. And c. D. C. Have been concerned about other potentially harmful ingredients in the vapor, as well as the effects of nicotine on the rainloping brains of adolescents. Nicotine is addictive, and no kid should be inhaling vapor bat contain nicotine into their lungs and possibly risking becoming addicted. Reporter from 2011 to 2015, ecigarette use increased from 1. 5 of High School Students to 16 . During that same period cigarette use dropped from 16 to 9 . P there a sense on your part that perhaps in the future those kids using ecigarettes might start smoking . The jury is still out on the gateway effects of ecigarettes, but we dont need the answer to the gateway question now to be able to conclude as a public calth matter that kids shouldnt be using ecigarettes in the first place. Up reporter manufacturers will have a grace period up to three years. After, that the f. D. A. Will begin enforcing regulations to prevent products from being sold j they dont meet requirements. Pelley dr. Jon lapook, thank you, doctor. What happened in syria today could only be called a war crime. Om least 28 people were killed, many women and children, in an air strike on a camp of defenseless refugees. It was in rebel territory near turkey. We dont know who fired the shot. These deaths add to the 320,000 who have been killed in five years of syrian civil war, but there is another cost, and that is the loss of irreplaceable history. The inheritance of all humanity. Inside syria, Elizabeth Palmer met the heroes in that fight. Reporter the music filled an tcient Roman Amphitheater that only three months ago was under itis control. It, like most of the ruins here, only survived that occupation by luck. But a trove of palmyras smaller treasures were saved by dedicated archaeologists, syrias very own monument men and women, led by chief of antiquities maamoun abdulkarim. Fs mission is to protect syrias heritage from all sides e the civil war. We met him among the empty display cases of the damascus archaeological museum. All these galleries its from the islamic period. Reporter right at the start of the fighting, he emptied and g,osed all of syrias antiquities museums. As for the priceless exhibits, some 300,000 objects, he and a very few trusted colleagues hid them. Will you tell me where . Gr no, never. We are just small group. Look here. Reporter but he did agree to show us photos of the crates in oueir secret hiding place. Maamouns greatest triumph came in palmyra. Ofs team managed to evacuate 99 of its Museum Artifacts to safety in damascus just as isis edlled into town. They destroyed several important buildings and laced the site toth explosives which had to be s refully detonated. Syrias civil war has kept its s easures off limits for more than five years now. But abdulkarim is quietly planning for peace, eventually. And the day concerts in the amphitheater are not just for the benefit of soldiers but once again open to the world. Elizabeth palmer, cbs news, damascus. Pelley investigators are learning more about the Health Issues suffered by prince. And passengers had a terrifying evight when the cbs evening news continues. Pelley two weeks after his death, we are learning new details about the health of rock legend prince. Jamie yuccas reports. Reporter the headline of todays Minneapolis Star Tribune percocet found in princes system prompted the medical examiner to push back caainst such media reports saying in a Statement Released late this afternoon, her office anynot released any information to anyone, including law enforcement. Law enforcement sources tell cbs news they are trying to determine the source of prescription pills found on prince and in his home. An attorney for howard kornfeld, a prominent drug Addiction Treatment doctor in northern california, says the doctor was contacted to help prince the day before the singers death. Isrnfeld sent his son, andrew, to minneapolis to facilitate treatment. William mauzy is kornfelds attorney. Andrews purpose in being there was to describe the recovery without walls program, to familiarize prince with that. Reporter instead, andrew was among the group that found prince unconscious in the elevator the next morning. Andrew kornfeld had in his possession an opioid treatment poug called buprenorphine. Dr. Shiela specker is an addiction specialist at the university of minnesota. Buprenorphine is used particularly for withdrawal, so a person may be on it to bethdrew from opioids, or they may be on it for maintenance. Reporter the medical examiners toxicology report setermining princes cause of death could come next week, but, scott, it could also be sealed ce to the ongoing criminal investigation. Pelley jamie yuccas near princes home tonight. Jamie, thank you very much. Extreme turbulence gave passengers a flight theyll never forget. Pet moments are beautiful, unless you have allergies. Flonase is the first and only nasal spray approved to relieve both itchy, watery eyes and congestion. No other nasal allergy spray can say that. Go ahead, embrace those beautiful moments. Flonase changes everything. Im phil mickelson, pro golfer. My Psoriatic Arthritis caused joint pain. 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Pelley passengers on a Etihad Airways jet had the tight of their lives yesterday in extreme turbulence over indonesia. Eporta nair has this. Reporter on this cell phone video, you can hear passengers praying, crying, and screaming as the airbus a330 violently shakes. The turbulence started 45 minutes before the flight was onheduled to land in jakarta. Nde shaking was so strong, that oxygen masks deployed, and diorage bins started to rip. Photos posted on social media by passengers showed food and garbage strewn all over the cabin. Nenden nurhaini was on the flight. In my group, there are three lejured people, she said. On the other group, some of them got injured on their legs and one of them got a severe head injury because of hitting the cabin ceiling. While the plane landed safely, more than 30 passengers and crew were injured, nine so seriously they were transported to the hospital. Inny suffered broken bones. Sae airline is considered to htve a good safety record. Urn t, this flight was supposed to return to abu dhabi, but has since been canceled. Pelley vinita nair, thanks very much. When we come back, the hall of fame jockey and the brother who got him back in the saddle. If youve gone to extremes to escape your nasal allergies. Try clarispray. New, from the makers of claritin. With the 1 prescribed ingredient. And nothing is more effective at relieving your sneezing, runny nose and nasal congestion. Return to the world with clarispray. Gaviscon is a proven heartburn remedy that gives you fastacting, longlasting relief. It immediately neutralizes acid and only gaviscon helps keep acid down for hours. For fastacting, longlasting relief, try doctorrecommended gaviscon. toilet flush if you need an opioid to manage your chronic pain, you may be sooo constipated it feels like everyone can go. Except you. Tried many things . Still struggling to find relief . You may have opioidinduced constipation, oic. 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I guess he takes after his mother. I take after my father. Reporter why do i get the sense that hes always the one who kind of keeps you in line . You have good senses, yes. Exaggerator, an absolutely brilliant victory reporter kent is a superstar. Tis a hall of fame jockey who has won the derby three times, but hes always been a partier and a drinker. Within the last five years he showed up inebriated before several races. He was fined and ordered to go to counseling. Few horsemen would hire him. It was this one who actually picked up the phone and said, e oy, you need to tighten up. So when i got to the fork in the road, big brother was like, you need to go right because youre , ing wrong. Y reporter kent is back in riding shape, and although still battling his demons, brother, keith, went to bat for him, convincing owners to give him another shot. There he is this saturday, kent will ride the derbys second favorite, exaggerator, trained by big brother keith. Did you think youd ever ride for him . Ur no, no. Its totally surreal. Secant even believe it. Nnhave to pinch myself. I cannot believe its my brother. Reporter you always looked up to him. Y forever, still do. Dont say always. Say still do. Hes my big brother. And theyre off reporter for kent, this run for the roses will be a ride for redemption. Dullehan and Kent Desormeaux and a chance to repay that big brother who bet on him when few others would. David begnaud, cbs news, louisville. Pelley there is help for tdiction. And thats the cbs evening news for tonight. For all of us at cbs news all around the world, good night. Captioning sponsored by cbs captioned by Media Access Group at wgbh access. Wgbh. Org new at 6 00, a sillicon valley Mayors Challenge to the worlds most valuable company. Why he says apple needs to step it up before it becomes a burden to its hometown. Apple has brought more negatives at this point. New at 6 00, squeezed out of the bay area. Texas scoops up yet another one of our businesses. I think california taxes the hell out of businesses. [ thunder ] this is what it looked like to have your home struck by lightning it was really scary. The bay area storm could cause a panic for schoolkids. 911, hello . A sugar high to help save lives . The bay area 911 operators who fought back against a junk food ban. And good evening to you, im allen martin. Im Elizabeth Cook in for veronica de la cruz. The mayor of cupertino is feeling the bite of apple. The last time he got on the tech giants campus he was snubbed and now he says the citys biggest Employer Needs to step up. We sent kpix 5s len ramirez to find out whats the beef all about, len. Reporter it may have to do with this building behind me, the apple spaceship campus to be completed by the end of the year there may be a reality check going through the city of cupertino the people who live here and the officials. It has the mayor doing something that almost no politicians ever do and thats go on the record to call out apple. You know, they are one of the biggest companies. People probably are afraid that they might move. Reporter cupertino mayor barry chang says dealing with apple can be intimidating but he said that didnt stop him from once trying to get and on the spot meeting. So i went to apple and i thought i can talk to the director or someone to see if theres anything i can help. But then apple reception was