Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders.

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,Rugang Zhang ,Christopherm Davis ,Xue Hao ,Kazuko Nishikura ,Emily Henderson ,Gene Expression Regulation Program At Wistar Ellen ,Ronald Caplan Cancer Center ,Microenvironment Metastasis Program ,Wistar Institute ,Nature Cell Biology ,Endowed Professor ,Metastasis Program ,Gene Expression ,Regulation Program ,Aging ,Nzyme ,Na ,Poptosis ,Autophagy ,Dancer ,Fell ,Cell Biology ,Mmunology ,Metastasis ,Mh ,Protein ,Research ,