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Precise activation and tracking of cancer treatment with a new compound is possible

This class of inhibitors has shown therapeutic promise in several cancer types, including chronic lymphocytic leukemia and Burkitt lymphoma ....

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Breakthrough discovery could lead to new treatments for brain metastases

When cancer that starts in the body metastasizes to the brain, it is almost always lethal, in part because so few treatment options exist. Now a new study by Wistar scientists published in Nature Communications shows that a type of brain cell called astrocytes plays an important role in promoting brain metastasis by recruiting a specific subpopulation of immune cells. ....

Lily Ramsey , Qing Chen , Ronald Caplan Cancer Center , Wistar Institute , Nature Communications , Microenvironment Metastasis Program , Image Credit , Metastasis Program , Brain Metastases , Brain Cell , Breast Cancer ,

Study gives new insight into how cancer metastasizes to the brain

Study gives new insight into how cancer metastasizes to the brain
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Weili Ma , Qing Chen , Nature Communications , National Cancer Institute , Wistar Institute , Ronald Caplan Cancer Center , Microenvironment Metastasis Program , Ingenuity Pathway , Metastasis Program ,

Wistar scientists reveal a novel ADAR1-SIRT1-p16INK4a axis in regulating cellular senescence

Aging and age-related disorders pose a complex challenge to the biomedical research community. To better understand how senescence is regulated is of high significance to promote healthy aging and treat age-associated disorders. ....

Rugang Zhang , Christopherm Davis , Xue Hao , Kazuko Nishikura , Emily Henderson , Gene Expression Regulation Program At Wistar Ellen , Ronald Caplan Cancer Center , Microenvironment Metastasis Program , Wistar Institute , Nature Cell Biology , Endowed Professor , Metastasis Program , Gene Expression , Regulation Program , Cell Biology ,

Wistar scientists discover a new way to boost a person's immune response to tumors

Due to the development of resistance to chemotherapy and recurring tumors, patients with ovarian cancer often have low survival rates. ....

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