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Taiwan company to present Phase II trial data for its COVID vaccine

The Wuhan lab lie and the political witch hunt against science

Over the past week, the US media and the Biden administration have sought to legitimize the conspiracy theory that the world’s leading scientists were engaged in a cover-up of the “Wuhan lab” origins of COVID-19.

Vascular Smooth Muscle Cells via JNK/c-JUN Pathway

Purpose: The deposition of hydroxyapatite (HAp) crystals plays an important role in the development of vascular calcification (VC). This study aimed to demonstrate the effects of nanosized HAp (nHAp) on vascular smooth muscle cells (VSMCs) and VC progression. Methods: Transmission electron microscopy (TEM) was used to examine cellular uptake of nHAp. Cell viability was determined using CCK-8 assay kit. Mitochondrial impairment and reactive oxygen species were detected by TEM and fluorescence dye staining, respectively. Cell apoptosis was detected by Western blot analysis and Annexin V staining. Mouse model of VC was built via applying nHAp on the surface of abdominal aorta. Calcification was visualized by Alizarin red and von Kossa staining.

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