These 12 individuals have a rare genetic quirk that prevents self-eating in cells livescience.com - get the latest breaking news, showbiz & celebrity photos, sport news & rumours, viral videos and top stories from livescience.com Daily Mail and Mail on Sunday newspapers.
As reported in
Science Translational Medicine, researchers pinpointed a protein called melanocortin 3 receptor (or MC3R) as an avenue for accessing the brain circuitry that controls the body’s energy balance and food intake.
The research offers preliminary evidence that manipulating the MC3R can either stimulate or suppress food intake.
The MC3R sits on the surface of neurons, where it sends and receives signals about the overall energy balance in the body. Although this protein is found throughout the brain, it is particularly prevalent in brain regions that are known to control feeding in both mice and humans.
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Courage Therapeutics has been awarded an STTR grant by the National Insittute of Mental Health to design novel anorexia drugs. The grant is a follow-up to research by the Cone lab at the University of Michigan that recently published in Science Translational Research that MC3R is a potential target for therapeutic development in anorexia and obesity. The effort allows for an expeditious translation of basic science into eating disorders which have remained an area of significant unmet need.
Newton, MA, April 23, 2021 (PR.com) Courage Therapeutics has been awarded a grant to design novel drug compounds to treat anorexia nervosa from the National Institute of Mental Health.
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