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1 antibody blocks dengue virus infection in mice

One antibody can block the ability of the dengue virus to cause disease in mice, researchers have found. The findings open the potential for developing effective treatments and designing a vaccine for dengue and similar diseases. Dengue virus, a member of a group of viruses called flaviviruses, causes 50 to 100 million cases of dengue disease each year, with no effective treatment or vaccine. Other members of this group include the viruses that cause Zika, yellow fever, and West Nile fever. As ...
United States Life Sciences Institute Scott Biering David Akey Janet Smith Keva Harris

New research reveals how one antibody blocks dangerous effects of dengue virus infection, offering a potential path to prevention

Date Time Share New research reveals how one antibody blocks dangerous effects of dengue virus infection, offering a potential path to prevention Researchers have revealed how one antibody (in green) is able to neutralize a protein that is central to the dengue virus’s ability to cause disease, by blocking the protein’s ability to interact with host cells. Image credit: Rajani Arora, U-M Life Sciences Institute A team of researchers has discovered an antibody that blocks the ability of the...
United States Life Sciences Institute Marcusp Wong Dustinr Glasner Michaelj Mina Janet Smith

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