As you grow older, some tests could be skipped
Marlene Cimons, The Washington Post
Dec. 19, 2020
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There s no shortage of advice on preventive medical tests people should have as they age, such as blood pressure screening and bone density scans. What s more confusing, however, and often tougher to figure out, are the ones they may be able to skip - and why. It s not a one-size-fits-all on any of these, says Paul Takahashi, a geriatrician with the Mayo Clinic. One of the more challenging things we talk about with our patients is when to stop doing a certain test. For a lot of people, it s very individualized, depending on their goals. Also, we live in a society where we don t have any evidence that doing more really helps you live longer.
As you grow older, some preventive medical tests can actually be skipped
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Frontline healthcare workers this week received some of the first doses of the Pfizer COVID-19 vaccine as part of the state’s strategy to distribute vaccines in limited supply.
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Frontline healthcare workers this week received some of the first doses of the Pfizer COVID-19 vaccine as part of the state s strategy to distribute vaccines in limited supply.
As Webster County Public Health ations the first precious shipments of the Pfizer-BioNTech COVID-19 vaccine, the public is urged not to abandon the precautions while Iowa remains on high alert with recent waves of cases.
“While we celebrate the first shipment of vaccine, we are many months away from being able to offer the vaccine to the public,” said Kelli Bloomquist, public information officer. “We must remain vigilant in practicing social distancing, wearing a mask, washing hands and staying home while sick. The vaccine is a historic scientific milestone, but we cannot forget that th
AAV Capsid-Promoter Interaction Shown to Occur in Non-human Primate Brain
December 11, 2020
The phenomenon of adeno-associated virus (AAV) capsid-promoter interaction recently seen in the rat central nervous system has now been shown to occur in the non-human primate brain. This interaction can directly determine cell-specific transgene expression, as described in the article, “Adeno-Associated Virus Capsid-Promoter Interactions in the Brain Translate from Rat to the Nonhuman Primate,” published in
Human Gene Therapy.
An AAV contains a single-stranded DNA genome encapsulated in a capsid comprised of three structural proteins.
“Recently, we established an AAV9 capsid-promoter interaction that directly determined cell-specific gene expression across two synthetic promoters, Cbh and CBA, in the rat striatum. These studies not only expand this capsid-promoter interaction to include another promoter in the rat striatum but also establish AAV capsid-promoter interactions in the
The epidemiologist sitting before the cameras spoke with calm authority. It was late March, and as the coronavirus spread across the United States, it came as no surprise that journalists were turning to John Ioannidis. The Stanford University medical professor was famous for his rigorous assessments – and frequent debunking – of disease treatments. He was a consummate physician-researcher, combining fluency in the mathematical models that predict a pathogen s lines of attack with experience at the bedsides of patients suffering from Aids. The surprise came in what Ioannidis had to say. As many public health experts and US government officials were urging people to stay home to avoid infection, he speculated that the coronavirus might be less dangerous than assumed. News media were overhyping the disease. The greater risk lay not in Covid-19 but in overzealous lockdowns to prevent its spread.
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