Half the individuals receiving the new CAR-T cell therapy achieved stable disease or better. Intratumoral, intraventricular, and intratumoral + intraventricular administration routes all were generally well tolerated. The Latest A recent phase 1 clinical trial by Brown et al. and funded by Mustang Bio and City of Hope investigated CAR-T cell therapy for the
Cognitive-behavioural therapy improves sleep in patients with mild cognitive impairment 1. In patients with mild cognitive impairment, empowerment-based cognitive behavioural therapy was shown to improve sleep and cognition after 6 months. 2. Patients receiving cognitive behavioural therapy had a greater reduction in insomnia and greater improvement in global cognition when compared to patients receiving standard
1. At-home eccentric exercise produced more improvement in muscular peak torque and gait speed than static stretching or dynamic closed-chain stretching. 2. At-home eccentric exercise, static stretching, and dynamic closed-chain stretching all improved hamstring flexibility and passive ankle dorsiflexion. Evidence Rating Level: 1b A large detriment of aging is the reduction of functional ability. A
1. In this cross-sectional study, there was a significant association between insufficient sleep duration and the presence of moderate or severe periodontitis and tooth loss. 2. Furthermore, both insufficient and excessive sleep were associated with increasing periodontitis. Evidence Rating Level: 3 (Average) Periodontitis is a highly prevalent condition and is the main cause of tooth
1. Docosahexaenoic acid supplementation at the in utero dose for infants born at less than 29 weeks gestation did not improve behavioral and emotional functioning at 5 years of age. 2. No differences in executive functioning or health were found between the children who had received high-dose docosahexaenoic acid and the children who had not.