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Phase 3 Maintenance Results Show Patients with Crohn's Disease Receiving Risankizumab (SKYRIZI®) Achieved Endoscopic Response and Clinical Remission at One Year

Phase 3 Maintenance Results Show Patients with Crohns Disease Receiving Risankizumab (SKYRIZI®) Achieved Endoscopic Response and Clinical Remission at One Year - In Crohns disease patients with clinical response to risankizumab IV induction treatment, a significantly greater proportion of patients treated with risankizumab 360 mg SC achieved endoscopic response and clinical remission at one year (52 weeks) versus those who were withdrawn from risankizumab (control group)[1] - The overall safet...
United States Gastroenterol Hepatol Access Economics Pty Drug Administration Boehringer Ingelheim Exchange Commission

Horizon Therapeutics plc Presents New Data on Robust Pipeline at EULAR European Congress of Rheumatology

Horizon Therapeutics plc Presents New Data on Robust Pipeline at EULAR European Congress of Rheumatology -- Early data from ongoing PROTECT trial suggest stable and durable response to KRYSTEXXA (pegloticase injection) therapy in treating uncontrolled gout among people with kidney transplants -- -- Data on the companys investigational compound (HZN-4920) under evaluation for rheumatoid arthritis will be presented during an oral session on June 3 at 10:15 a.m. CEST -- Horizon Therapeutics plc (N...
United States Amanda Phraner Ruth Venning Tina Ventura Jeffreyd Kent Ray Gordon

U.S. Food and Drug Administration Approves Bristol Myers Squibb's Zeposia® , an Oral Treatment for Adults with Moderately to Severely Active Ulcerative Colitis1

Zeposia the first and only oral sphingosine 1-phosphate receptor modulator approved for ulcerative colitis 1 represents a new way of treating this chronic immune-mediated disease 2 Zeposia demonstrated significant improvements across all primary and key secondary efficacy endpoints including clinical remission, clinical response, endoscopic improvement and endoscopic-histologic mucosal improvement versus placebo at ...
United States Feaganb Ozanimod Bristol Myers Squibb Michael Chiorean Adam Lenkowsky National Institute Of Diabetes

Investegate |NOVARTIS AG CHF0.50(REGD) Announcements | NOVARTIS AG CHF0.50(REGD): Novartis reports one year results of Phase III MERLIN study evaluating Beovu® every four week dosing and provides update on Beovu clinical program

NOVARTIS AG CHF0.50(REGD) Novartis reports one year results of Phase III MERLIN study evaluating Beovu® every four week dosing and provides update on Beovu clinical program Novartis reports one year results of Phase III MERLIN study evaluating Beovu® every four week dosing and provides update on Beovu clinical program Beovu (brolucizumab) met MERLIN’s primary endpoint of non-inferiority in change in best corrected visual acuity from baseline and superiority on anatomical secondary endpoints...
United States United Kingdom Isabella Zinck Rachel Fink Lookeren Campagne Thomas Hungerbuehler

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Novartis Pharma AG: Novartis reports one year results of Phase III MERLIN study evaluating Beovu every four week dosing and provides update on Beovu clinical program

Beovu (brolucizumab) met MERLIN's primary endpoint of non-inferiority in change in best corrected visual acuity from baseline and superiority on anatomical secondary endpoints at year one versus aflibercept
United States United Kingdom Isabella Zinck Rachel Fink Lookeren Campagne Thomas Hungerbuehler

Horizon Therapeutics plc Initiates ADVANCE Trial Evaluating KRYSTEXXA (pegloticase injection) with Methotrexate for People Who Previously Developed Anti-Drug Antibodies on KRYSTEXXA Monotherapy

(0) -- Trial evaluates opportunity to improve outcomes based on emerging data that immunomodulation may offer clinical benefit -- Horizon Therapeutics plc (Nasdaq: HZNP) today announced the first patient has enrolled in the ADVANCE trial evaluating the concomitant use of KRYSTEXXA (pegloticase injection) with methotrexate for people with uncontrolled gout who were not able to achieve a complete response when previously treated with KRYSTEXXA monotherapy. For people with chronic gout refractory ...
University Of Southern California United States Santa Monica Amanda Phraner Ruth Venning Tina Ventura

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