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COVID-19 and lung cancer have a common pathway, say researchers The coronavirus disease 2019 (COVID-19) is a transmissible viral disease caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the pathogen responsible for the ongoing global pandemic. The virus was first detected in Wuhan, China, at the end of 2019 and to date has caused over 109 million infections worldwide. With over 2.4 million deaths, this virus can cause severe disease in certain high-risk groups such as...

A new preprint on the bioRxiv* server describes the development of a live attenuated vaccine candidate to counter the growing threat of the COVID-19 pandemic.

A team of scientists from Australia and Brazil recently investigated the involvement of endothelial cells in the pathogenesis of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection.

Strong immune response may increase susceptibility to Covid-19 in some cases February 17, 2021 Researchers in Berlin have observed how SARS-CoV-2 uses an immune system defense mechanism to multiply. The study, published in the journal EMBO Molecular Medicine, carried out by the researchers revealed that SARS-CoV-2 increasingly hijack the body’s mucous membrane cells and multiply there. “This may give us part of the explanation as to why the immune system has difficulty regulating or even ...

In a recent study conducted at the Indian Institute of Science Education and Research, India, a team of scientists screened specific genes of SARS-CoV-2 to identify factors that may contribute to viral infectivity.

How SARS-CoV-2 enters the central nervous system The central nervous system (CNS) is highly protected in the human body. Yet, the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) invades the CNS, causing profound clinical complications. How is the CNS involved in a respiratory virus infection? To understand this, researchers Ruqaiyyah Siddiqui, Mohammad Ridwane Mungroo and Naveed Ahmed Khan reviewed reported case studies and identified potential brain regions that may be affected by...

Mink-derived SARS-CoV-2 mutations reduce antibody effectiveness The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is thought to be a disease originally occurring in animals but transmitted across the species barrier to human beings, probably through an intermediate host. Following human infection, the virus has been shown to transmit to some pet and farm animals, where it then mutates. A new preprint research pa...

Researchers in France report impaired neutralization of two new SARS-CoV-2 variants by antibodies induced by vaccination or natural infection.

As the exact zoonotic origin of SARS-CoV-2 remains unresolved, scientists at the Francis Crick Institute in London, UK, explored the structure and binding properties of a Pangolin coronavirus spike glycoprotein to see if it could shed light on the evolution of SARS-CoV-2.

Now, a new preprint research paper posted to the bioRxiv server reports the development of a modified mouse model that allows productive SARS-CoV-2 infection of the mouse lungs, as well as the exploration of type I and III interferon responses in this condition.