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Protein deficiency, not age or weather, drives Covid-19 pandemic: Report

Protein deficiency, not age or weather, drives Covid-19 pandemic: Report February 10, 2021 ร— The study revealed that it was not the age factor or weather condition that should be blamed for the unchecked spread of the coronavirus According to a new study carried out by researchers from the National Institute of Biomedical Genomics-Kalyani, protein deficiency led to the rapid spread of Covid-19 in Europe and the United States. The study revealed that it was not the age factor or weather conditi...
India General United States Nidhan Biswas National Institute Of Biomedical Genomics National Institute Biomedical Genomics Kalyani

COVID-19 pandemic and nanotechnology

COVID-19 pandemic and nanotechnology In December 2019, a โ€˜viral pneumonia of unknown causeโ€™ was identified in Wuhan, China, which was later identified as the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). SARS-CoV-2 infection causes COVID-19 (coronavirus disease 2019) and is characterized predominantly by cough, fever, fatigue, and acute respiratory distress syndrome (ARDS) associated with high mortality rates. On March 11, 2020, the World Health Organization (WHO) officially...
South Korea Dongki Yang Ramya Dwivedi Gachon University World Health Organization Department Of Physiology

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Alpaca nanobodies neutralize SARS-CoV-2 in vitro

A new preprint research paper posted to the bioRxiv server reports the development of highly effective neutralizing nanobodies targeting the viral receptor-binding domain (RBD), thus disrupting its engagement with the host cell angiotensin-converting enzyme 2 (ACE2) receptor.
Liji Thomas Hetero Bivalent Alpaca Nanobodies Targeting Spike Receptor Binding Image Credit In Vitro Sars Cov 2

New platform using green algae tests for SARS-CoV-2 virus

Researchers at the University of California, San Diego, have demonstrated the potential of using green algae to make recombinant viral proteins that could be used in large scale assays to detect antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - the agent that causes coronavirus disease 2019 (COVID-19).
United States San Diego Sally Robertson Stephen Mayfield University Of California Sars Cov 2

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2

Elevated ACE2 and inflammation levels increase risk for pregnant women infected with SARS-CoV-2 Among the hundred million or so cases of coronavirus disease 2019 (COVID-19) that have occurred since the pandemic began, pregnant women have been a conspicuous risk group. However, the exact nature of the risk they and their fetuses face, and the mechanism by which it operates, is far from clear. A new preprint research paper posted to the medRxiv* server throws some light on this area by revealing...
Liji Thomas Natalia Grevtsova Shutterstock Natalia Grevtsova Sars Cov 2 Angiotensin Converting Enzyme 2 Corona Virus

Urinary shedding of spike protein in COVID-19 patients

A team of scientists from the United States has recently revealed that about 25% of people with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection develop renal complications and that the viral spike protein can be detected in the urine samples of these patients. The study is currently available on the medRxiv* preprint server.
United States Sanchari Sinha Dutta Kateryna Kon Shutterstock Kateryna Kon Spike Protein Angiotensin Converting Enzyme 2

Synergistic effect between NF-κB inhibitors and zinc in vitro reducing ACE2 expression

Synergistic effect between NF-ฮบB inhibitors and zinc in vitro reducing ACE2 expression Researchers at National Taiwan University Hospital in Taipei have conducted a study demonstrating the potential effectiveness of a novel drug combination at reducing morbidity and mortality in coronavirus disease 2019 (COVID-19). In a study using two human cell lines, a combination of the clinical drugs triclabendazole and emetine effectively suppressed expression of the host cell receptor for severe acute r...
National Taiwan University Hospital T Ai Pei Sally Robertson Researchers At National Taiwan University Hospital Drug Administration Bor Ru Lin

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