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October 20, 2023
In primary care setting, low-dose amitriptyline as second-line treatment improved IBS severity
May 4, 2021
email article The natural history of irritable bowel syndrome (IBS) defined according to the stricter Rome IV criteria is more severe than that of Rome III-defined IBS, a longitudinal study found. This has important implications for patient selection in future treatment trials, according to the investigators, led by Alexander C. Ford, MD, of the Leeds Gastroenterology Institute in England. As shown in the teams 12-month follow-up study published online in Clinical Gastroenterology and He...