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A cancer link to obesity: A metabolic tug-of-war - INDIA New England News

A cancer link to obesity: A metabolic tug-of-war The Harvard Gazette Obesity has been linked to increased risk for over a dozen different types of cancer, as well as worse prognosis and survival. Over the years, scientists have identified obesity-related processes that drive tumor growth, such as metabolic changes and chronic inflammation, but a detailed understanding of the interplay between obesity and cancer has remained elusive. Now, in a study in mice, Harvard Medical School (HMS) research...
Cong Hui Yao Vikram Juneja Gregory Baker Carlene Sharpe Jefte Drijvers Alison Ringel

Obesity Impairs Immune Cell Function in Cancer, Triggers Tug-of-War for Fuel

Obesity Impairs Immune Cell Function in Cancer, Triggers Tug-of-War for Fuel December 10, 2020 Source: Science Artwork/Science Photo Library/Getty Images Research by a Harvard Medical School (HMS)-led research team has uncovered a new mechanism by which obesity can interfere with the immune systemโ€™s ability to fight cancer. Their studies demonstrated how, in tumor-bearing mice fed a high-fat diet, cancer cells reprogram their metabolism in response to the increased fat availability, so they c...
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