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Molecular Switch Identified That Flips from Self-Renewal to Specialization in the Making of a Kidney

Molecular Switch Identified That Flips from Self-Renewal to Specialization in the Making of a Kidney April 5, 2021 Share Self-renewal and specialization are two opposing functions in progenitor cells. Scientists resolve the mechanisms behind the opposing developmental actions of beta-catenin, a co-activator of the established molecular Wnt signaling pathway, that paradoxically regulates both self-renewal and specialization of mammalian progenitor cells destined to become kidney cells. The new s...
Andrew Mcmohan Helena Bugacov Mcmahon Lab Keck School Southern California மக்மேயந் ஆய்வகம்

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