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Subcutaneous Amivantamab Is Associated With Increased Tolerability in Solid Tumors

Anna Minchom, MB BCh, MRCP, MD, discusses the need to develop an amivantamab administration method that decreases the likelihood of infusion-related reactions in patients with solid tumors, revealed the RP2D of subcutaneous amivantamab that was determined in the PALOMA trial, and emphasized potential future directions with this agent.
City Of United Kingdom Anna Minchom Institute Of Cancer Research Drug Development Lung Units

Study shows new cancer treatment can stop the disease advancing in patients who are resistant to immunotherapy

A new study has shown that a new cancer treatment can stop the disease from advancing in patients who are out of options, which includes being resistant to immunotherapy. Some tumours can evolve to resist immunotherapy which uses the immune system to target and kill cancer cells. Combining immunotherapy with guadecitabine can reverse cancer’s resistance to the former, according to oncologists in the UK.
United Kingdom Anna Minchom Institute Of Cancer Research Cancer Research Royal Marsden Prof Johann De Bono

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Drug combination shows promise against cancer's 'death star' protein

A drug combination targeting multiple mutant versions of cancer’s ‘death star’ protein has shown promise in a small, early-phase clinical trial for some patients with advanced lung, ovarian and thyroid cancer. The two-drug combination was effective against advanced cancers with a range of mutations to the ...
United States City Of United Kingdom Udai Banerji Anna Minchom American Society Of Clinical Oncology

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