Page 52 - Application Note News Today

UPM Biomedicals gives an overview of its GrowDex® 3D cell culture hydrogels

The EPA has been monitoring organic pollutants within wastewater matrices since 1984 by developing their own methods and acceptance criteria. The basic, neutral and acidic extractions in EPA Method 625.1 are a part of the revised version of EPA Method 625. In this application note, Biotage shows recoveries of all the analytes within tables 1–2 of 625.1 and a few analytes from table 3 obtained using the Biotage ® Horizon 5000 with Atlantic ® 8270 One Pass solid phase extrac

MembraPure gives an overview of its water purification systems available for each lab application.

RNA isolation is a challenging procedure. Unlike DNA, which is highly stable, RNA is very unstable, quickly digested by RNase enzymes if their activity isn’t immediately inhibited. One popular reagent in RNA isolation protocols is TRIzol ® . TRIzol was specifically formulated to isolate total RNA from any sample type in the modern research laboratory, whether in academia or industry: cells, hard to ly

Therapeutic Drugs of Abuse testing for critical point-of-care treatment, such as in drug treatment facilities or pain clinics, has traditionally been arduous, expensive and time consuming, requiring a third-party laboratory for analysis. Due to these factors, on-site liquid chromatography (LC) analysis at the local clinic is a requisite for timely evaluation and effective treatment. A point-of-care LC system must be easy to use, self-contained, safe for the

In this application note, Axcend shows how the MDAnalyzer™ can be used to quantify Metal Deactivator Additive (MDA) in jet fuel. the MDAnalyzer is a portable analyzer able to provide real time determination of the presence and specific concentration of MDA in an aviation turbine fuel sample at installation level or in a field environment outside of a laboratory.

Radio-telemetry monitoring of blood pressure, heart rate, ECG, temperature, and activity

In this application note, Axcend demonstrates the use of hand-portable capillary HPLC by the Axcend Focus LC for intact protein analysis. Specifically, the separation of five test proteins in the range of 5.8 to 45 kDa is shown using reversed phase (RP) conditions. Other protein samples can be analyzed using the Axcend Focus LC merely by adapting established conventional high performance LC methods to the capillary column format.

Immunotherapies such as CAR T cells that have shown success in treating liquid tumors have had limited efficacy against solid tumors, including glioblastoma. Natural killer (NK) cells represent a promising approach for solid tumor treatment, and understanding mechanisms of NK-mediated cytotoxicity is important for cell therapy development. In this application note, Axion Biosystems quantifies the kinetics of both antibody-dependent cellular cytotoxicity (ADCC) and CAR NK-mediated cytolysis a

Trastuzumab promotes natural killer cell activation through antibody-dependent cellular cytotoxicity (ADCC). Understanding ADCC can help researchers develop immunotherapies with better targeting and efficacy. In this application note, Axion Biosystems examines and quantifies ADCC-specific killing using the monoclonal antibody trastuzumab and peripheral blood natural killer cells on the Maestro z. The ADCC response between donors and across multiple effector to target cell ratios is compared.