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Monitoring of T-cell invasions assay on a 3D spheroid model

Workflow for the generation of 3D tumor spheroids, co-cultured with T-cells as a proof-of-concept model for CAR T assays

Application-note
Molecular-devices
T-cell
Part-cells
Achine-learning
Workflow-development
Umors

Quantifying NK-mediated cytolysis of glioblastoma in vitro with Maestro Z

Immunotherapies such as CAR T cells that have shown success in treating liquid tumors have had limited efficacy against solid tumors, including glioblastoma. Natural killer (NK) cells represent a promising approach for solid tumor treatment, and understanding mechanisms of NK-mediated cytotoxicity is important for cell therapy development. In this application note, Axion Biosystems quantifies the kinetics of both antibody-dependent cellular cytotoxicity (ADCC) and CAR NK-mediated cytolysis a

Axion-biosystems
Application-note
Maestro-z
Glioblastoma
Nk-cells
Part-cells
Axion-biosystems

Chimeric Antigen Receptor CAR T Cells

T cells engineered to express chimeric antigen receptors, commonly known as CAR T cells, have demonstrated the ability to help patients suffering from blood cancer.

United-states
New-jersey
Piscataway
Channabasavaiah-gurumurthy
Theodore-roth
Maria-osipova
Alexander-marson
Nat-protoc
University-of-nebraska-medical-center
Sponsored-content
Image-credit
Nebraska-medical-center

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