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CNN CNN News Central July 2, 2024

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Daily home-based low-volume paracentesis associated with greater risk of complications

1. For patients with refractory ascites, daily home-based low-volume paracentesis was associated with a greater risk of hyponatremia and acute kidney injury compared to repeated large-volume paracentesis. Evidence Rating Level: 3 (Average) Refractory ascites is a clinical sign of end-stage liver disease, with few effective treatment options. Most patients will undergo repeated large-volume paracentesis (LVP)
Minute Medicine Inc Rating Level Liver Disease Chronic Disease

Small vesicles released by intestinal bacteria induce immune activation and progression of liver cirrhosis

Researchers from Niigata University and Kyoto Prefectural University have revealed that small vesicles, around 100 nm in size, released by intestinal bacteria induce immune activation and progression of liver cirrhosis, as well as reduction of serum albumin level, subsequently leading to edema and ascites.
Atsunori Tsuchiya Emily Henderson Kyoto Prefectural University Division Of Gastroenterology Research Center Niigata University

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