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Purified exosomal product accelerates wound healing in preclinical models

Purified exosomal product accelerates wound healing in preclinical models Difficult-to-treat, chronic wounds in preclinical models healed with normal scar-free skin after treatment with an acellular product discovered at Mayo Clinic. Derived from platelets, the purified exosomal product, known as PEP, was used to deliver healing messages into cells of preclinical animal models of ischemic wounds. The Mayo Clinic research team documented restoration of skin integrity, hair follicles, sweat gland...
Atta Behfar Steven Moran Emily Henderson Drug Administration Mayo Clinic Center Mayo Clinic

Reverse-order heart-liver transplant helps prevent rejection for certain patients

ย E-Mail ROCHESTER, Minn. -- All too often, patients with high levels of antibodies face major challenges getting a transplant. These highly sensitized patients have a much higher risk of death while waiting for suitable organs they are less likely to reject. But there is new hope for highly sensitized patients in need of a combined heart and liver transplant, thanks to an innovative surgical approach at Mayo Clinic. Traditionally, surgeons transplant the heart first, followed by the liver. But...
Shannon Dunlay Richard Rodeheffer Alfredo Clavell Charles Rosen Joseph Dearani Andrew Rosenbaum

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