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'CAR T cells can eradicate solid tumors,' study in advanced neuroblastoma shows

A novel chimeric antigen receptor T-cell therapy induced clinically impactful antitumor responses in 63% of younger patients with relapsed or refractory, high-risk neuroblastoma, results of a phase 1/phase 2 trial showed.The findings, published in The New England Journal of Medicine, suggest the investigational agent also has a manageable safety profile similar to other CAR T-cell therapies,
United States Baylor College Of Medicine Oladapoo Yeku Danl Longo Ascendis Pharma Piazza Santonofrio
Source: healio.com

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Sanofi hits reset on drug from $2.5B deal after 'lower than projected' efficacy in trials

Sanofi did not see the efficacy it wanted in mid-stage tests of a cytokine therapy from its $2.5 billion acquisition of Synthorx. While the pharmaceutical giant isn’t giving up on the drug, it said it will restart the molecule in a new Phase 1/2 program, a setback that will lead to a €1.6 billion financial writedown.
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