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Researchers publish the first comprehensive, 3D analysis of the complete rhabdomyosarcoma genome

In a paper published in NAR Cancer, researchers from the Center for Childhood Cancer Research at Nationwide Childrens and their collaborators report a comprehensive 3D chromatin structural analysis and characterization of rhabdomyosarcoma (RMS). RMS is a pediatric soft-tissue tumor that predominantly affects children between 0 and 4 years, but it can also affect adolescents. Survival rates vary dramatically from 10% to 90% depending on the stage and subtype.
Meng Wang Benjamin Stanton Stanton Lab Childhood Cancer Research At Nationwide Children Childhood Cancer Research Nationwide Children

MFCR awards new grants to support an emerging approach to cancer therapeutics

MFCR awards new grants to support an emerging approach to cancer therapeutics The Mark Foundation for Cancer Research (MFCR) has awarded five new grants in support of an important, emerging approach to cancer therapeutics. The projects are centered around the molecular strategy of induced proximity, which involves controlling the physical distance between proteins to regulate or perturb biological processes in the cancer cell. One of the biggest challenges in developing new cancer therapies is ...
United States H Courtney Hodges Michele Cleary Benjamin Stanton Nate Hathaway Becky Bish

The Mark Foundation awards grants to accelerate new class of cancer drugs based on induced proximity

 E-Mail NEW YORK - The Mark Foundation for Cancer Research (MFCR) has awarded five new grants in support of an important, emerging approach to cancer therapeutics. The projects are centered around the molecular strategy of induced proximity, which involves controlling the physical distance between proteins to regulate or perturb biological processes in the cancer cell. One of the biggest challenges in developing new cancer therapies is that many proteins are not tractable to the traditional a...
United States H Courtney Hodges Michele Cleary Benjamin Stanton Nate Hathaway Becky Bish

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