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Piroxicam may augment the clinical efficacy of levonorgestrel in emergency contraception

1. Levonorgestrel plus piroxicam resulted in significantly fewer pregnancies compared to placebo. 2. There were no changes with respect to menstrual cycle advancement or delay in each group. Evidence Rating Level: 1 (Excellent) Study Rundown: Levonorgestrel is a commonly used emergency contraceptive; however, its therapeutic benefits require it to be used prior to ovulation. Whether
Hong Kong Rating Level Intrauterine Devices Between Aug Emergency Contraception Women 039s Health

Use of dual antibiotic loaded cement does not reduce surgical site infection rates in patients undergoing hemiarthroplasty

1. Deep surgical site infection at 90 days was 1.7% in the single-antibiotic group versus 1.2% in the dual-antibiotic loaded cement group, with no significant differences between groups. 2. Quality of life, mobility, and mortality at 120 days were comparable between both groups. Evidence Rating Level: 1 (Excellent) Study Rundown: Hip fracture is a common
United Kingdom Uncemented Hemiarthroplasty Rating Level Intracapsular Hip Between Aug High Dose Dual Antibiotic Loaded Cement

#VisualAbstract: Low-molecular-weight heparin does not improve live birth rates in women with recurrent pregnancy loss and thrombophilia

1. Live birth rate between the low-molecular-weight heparin and standard care group was comparable. 2. The most common inherited thrombophilia were heterozygous Factor V Leiden followed by heterozygous Prothrombin G20210A mutations. Evidence Rating Level: 1 (Excellent) Study Rundown: Thrombophilia is a leading cause of recurrent miscarriage around the world. Although anticoagulant therapy may reduce the number of
United States United Kingdom Between Aug Factorv Leiden Pregnancy Loss

Fruquintinib significantly improves survival in patients with refractory metastatic colorectal cancer

1. Overall survival was significantly greater in the fruquintinib group versus placebo. 2. The majority of adverse events were mild-to-moderate and were slightly more common among patients receiving fruquintinib. Evidence Rating Level: 1 (Excellent) Study Rundown: Colorectal cancer is the third-most prevalent cancer in the world and the second leading cause of death worldwide. Patients
Rating Level Colonoscopy Screening Colorectal Cancer Between Aug Colon Cancer Metastatic Colorectal Cancer

Low-molecular-weight heparin does not improve live birth rates in women with recurrent pregnancy loss and thrombophilia

1. Live birth rate between the low-molecular-weight heparin and standard care group was comparable. 2. The most common inherited thrombophilia were heterozygous Factor V Leiden followed by heterozygous Prothrombin G20210A mutations. Evidence Rating Level: 1 (Excellent) Study Rundown: Thrombophilia is a leading cause of recurrent miscarriage around the world. Although anticoagulant therapy may reduce the
United Kingdom United States Factorv Leiden Rating Level Suspected Pulmonary Between Aug

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