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Researchers map brain cell changes in Alzheimer's disease | MIT News | Massachusetts Institute of Technology

A study by scientists at MIT and at the Broad Institute of MIT and Harvard shows how brain cells located near amyloid plaques and tau tangles change as Alzheimerโ€™s disease progresses. The technique, called STARmap PLUS, is the first to simultaneously map gene expression of individual cells and their location, as well as the spatial distribution of specific proteins in intact tissue samples.
Morgan Sheng Zhaowen Zhou Xiao Wang Jiahao Huang Broad Institute Psychiatric Research
Source: mit.edu

Using light to manipulate neuron excitability

MIT and Harvard University researchers have devised a way to achieve long-term changes in neuron activity. With their new strategy, they can use light exposure to change the electrical capacitance of the neuronsโ€™ membranes, which alters their excitability (how strongly or weakly they respond to electrical signals).
Jia Liu Wenbo Wang Xiao Wang Yiming Zhou Broad Institute Harvard University Materials Research Science
Source: mit.edu

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