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High-dose opioid reversal spray no better than lower dose in field, US study finds

The analysis also suggests that those given the higher 8 milligram strength spray were more than twice as likely to experience opioid withdrawal symptoms compared to other sprays such as Narcan that use a 4 mg dose. The Hikma version, sold under the brand name Kloxxado, was approved in 2021 after U.S. Food and Drug Administration advisers and National Institutes of Health reports suggested that a high-dose version was needed to respond to overdoses by more potent opioids such as fentanyl. The ...
New York United States Biosolution Narcan Caroline Humer Padagis Israel Pharmaceuticals Us Centers For Disease
Source: yahoo.com

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