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Valley News - Valley News Forum for May 26, 2023: Lebanon's Science Olympiad success was a team effort

Lebanon’s Science Olympiad success was a team effortAs the coach of the Lebanon High School Science Olympiad team, I would like to express my thanks and gratitude, on behalf of our students, to the stakeholders in our community who have been so...
United States White River Junction New Hampshire Lebanon High School John Tietjen Hartford Selectboard
Source: vnews.com

Tech Tidbits From Around New Hampshire - NH Business Review

NH Business Review NH companies attract investment and recognition ... and more May 27, 2021 MilliporeSigma’s launches new synthetic cholesterol product, which could be used in mRNA therapeutics, including Pfizer-BioNTech Covid-19 Vaccine. MilliporeSigma has launched a new product nine months ahead of schedule in order to meet what it says is the high demand for lipids, a key component of mRNA-based vaccines and therapeutics. The German manufacturer, which has a location in Jaffrey, NH, is ma...
New Hampshire United States Biontech Covid Susquehanna Growth Equity International Organization For Standardization Community College System
Source: nhbr.com

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B7-H3×4-1BB bispecific antibody augments antitumor immunity by enhancing terminally differentiated CD8+ tumor-infiltrating lymphocytes

Abstract Cancer immunotherapy with 4-1BB agonists has limited further clinical development because of dose-limiting toxicity. Here, we developed a bispecific antibody (bsAb; B7-H3×4-1BB), targeting human B7-H3 (hB7-H3) and mouse or human 4-1BB, to restrict the 4-1BB stimulation in tumors. B7-H3×m4-1BB elicited a 4-1BB–dependent antitumor response in hB7-H3–overexpressing tumor models without systemic toxicity. BsAb primarily targets CD8 T cells in the tumor and increases their proliferati...
United States South Korea Republic Of Korea Tonbo Biosciences Eomes Dan Spectrostar Nano

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