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22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia

22 blood plasma lipids found to be associated with lower symptom improvement in schizophrenia Researchers from Skoltech and the Mental Health Research Center have found 22 lipids in the blood plasma of people with schizophrenia that were associated with lower symptom improvement over time during treatment. These can help track resistance to medication that affects over a third of patients. The paper was published in the journal Biomolecules. Studies suggest that up to 34% of people living with...
Anna Tkachev Emily Henderson Mental Health Research Center Skoltech Center Brain Restoration Negative Syndrome Scale

New Feature That Contributed to Modern Humans Evolving Away From Neanderthals Is Discovered

Read Time: Skoltech scientists and their colleagues from Germany and the United States have analyzed the metabolomes of humans, chimpanzees, and macaques in muscle, kidney, and three different brain regions. The team discovered that the modern human genome undergoes mutation which makes the adenylosuccinate lyase enzyme less stable, leading to a decrease in purine synthesis. This mutation did not occur in Neanderthals, so the scientists believe that it affected metabolism in brain tissues a...
Nordrhein Westfalen United States Philipp Khaitovich Vita Stepanova University Of Denver Skoltech Center

Scientists discover new feature that distinguishes modern humans from ancient Neanderthals

Scientists discover new feature that distinguishes modern humans from ancient Neanderthals Led by Professor Philipp Khaitovich, this new feature distinguishing modern humans from Neanderthals has been discovered by Skolteck scientists Ghost Population A new feature that distinguishes modern humans from Neanderthals has been discovered by Skolteck scientists after examining the metabolism of humans, chimpanzees, and macaques in the muscle, kidney, and three separate brain areas. Researchers from...
Pavel Odinev Skoltech Philipp Khaitovich Vita Stepanova University Of Denver Skoltech Center Neanderthal Museum

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Scientists discover a new feature that distinguishes modern humans from Neanderthals

Credit: Pavel Odinev / Skoltech Skoltech scientists and their colleagues from Germany and the United States have analyzed the metabolomes of humans, chimpanzees, and macaques in muscle, kidney, and three different brain regions. The team discovered that the modern human genome undergoes mutation which makes the adenylosuccinate lyase enzyme less stable, leading to a decrease in purine synthesis. This mutation did not occur in Neanderthals, so the scientists believe that it affected metabolism i...
Nordrhein Westfalen United States Philipp Khaitovich Vita Stepanova University Of Denver Skoltech Center

Skoltech team completes a large-scale study into the role of RNA maturation for organ development

 E-Mail Researchers from Russia and Germany have created a genome-wide atlas of developmental alternative splicing changes of seven organs in six mammal species and chicken. The research was published in the journal As the protein encoding RNA matures in eukaryotes, it gets spliced, with some parts cut out and the remaining fragments stitched together. Alternative splicing means that the same RNA fragment can either be cut out from or kept within the mature RNA. In this case, one gene can enc...
Baden Wüberg Pavel Mazin Philipp Khaitovich University Of Heidelberg Germany Skoltech Center Brain Restoration

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