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Scientists unravel the workings of a mysterious protein implicated in movement disorders

Scientists unravel the workings of a mysterious protein implicated in movement disorders Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders. The findings, which appear in Cell Reports, are an advance in the basic understanding of how the brain controls muscles and could lead to treatments for children born with Gαo-mutation movement disorders...
United States Brian Muntean Kirill Martemyanov Emily Henderson Scripps Research Bow Foundation

Unraveling the mystery of Gao, a protein implicated in movement disorders

 E-Mail Scientists at Scripps Research have clarified the workings of a mysterious protein called Gαo, which is one of the most abundant proteins in the brain and, when mutated, causes severe movement disorders. The findings, which appear in Cell Reports, are an advance in the basic understanding of how the brain controls muscles and could lead to treatments for children born with Gαo-mutation movement disorders. Such conditions--known as GNAO1-related neurodevelopmental disorders--were dis...
United States Stefano Zucca Dipak Patil Kirill Martemyanov Lutz Birnbaumer Randy Blakely

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