Bryanl Roth News Today

The discovery by UNC School of Medicine researchers should not impact life-saving use of naloxone for opioid overdoses.

Unregulated use of fentanyl and overdose deaths have increased dramatically in recent years, and this trend was made more alarming when authorities found fentanyl laced with the animal tranquilizer xylazine.

In the continuing effort to improve upon opioid pain relievers, American and Chinese scientists used cryoEM technology to solve the detailed structures of the entire family of opioid receptors bound to their naturally occurring peptides.

Understanding of how neuronal activity modulates brain function is a key first step towards creating more effective drugs to treat a variety of neuropsychiatric illnesses, including depression, anxiety, schizophrenia, substance abuse, epilepsy, and others.

While illegal for recreational use, psychedelic drugs are showing great promise as treatments for severe depression and anxiety, as well as alcohol addiction and other conditions.

A research team from UNC-Chapel Hill, UC San Francisco, Yale, Duke and Stanford developed a new compound that hits the same brain cell target as psychedelic drugs, triggering long-lasting antidepressant action without psychedelic effects.

The Iowa State Patrol has identified 60-year-old Annie Zleh, of Muscatine, as the victim killed in a crash Sunday in Johnson County.

V-SYNTHES is a new computational method for analyzing billions of theoretical compounds as candidates for therapeutic drugs.

On the surface of our cells are docking stations called receptors. All kinds of compounds from caffeine and dopamine to heroin, THC and LSD bind to