Byrobert Stott News Today

WASHINGTON — Glucagon-like peptide-1 receptor agonists significantly reduced alanine aminotransferase levels in pediatric metabolic dysfunction-associated steatotic liver disease, especially those with type 2 diabetes, researchers reported. “The study was prompted by my interest in the use of anti-obesity medications in the treatment of MASLD,” Jennifer A. Panganiban, MD,

WASHINGTON — Nearly 60% of patients with acute severe ulcerative colitis responded to Xeljanz 10 mg twice daily by day 7, with one-third of patients in steroid-free remission by 6 months, according to interim analysis data presented here. “There are few recommended therapies for acute severe UC management given the need for rapidly acting therapies,” Neeraj Narula, MD, MPH,

WASHINGTON — Oral antibiotic use among adult patients was not associated with increased risk for early-onset colorectal cancer, according to data presented at Digestive Disease Week. “The incidence of early-onset colorectal cancer is increasing over the past 3 decades; however, little is known about what may be driving this increase in early-onset CRC,” Jeffrey K. Lee, MD, MPH,

WASHINGTON — Although a greater number of patients with Crohn’s disease who failed anti-TNF therapy achieved biologic remission with Skyrizi vs. Stelara, choosing between the two therapies “still remains on the table,” a researcher noted. Skyrizi (risankizumab, AbbVie) previously demonstrated noninferiority for clinical remission at week 24, and superior endoscopic

WASHINGTON — Provider recommendation was a major influencer for colonoscopy screening for young adults at average risk for colorectal cancer, especially non-Hispanic Black patients, according to data presented at Digestive Disease Week. “Screening rates are low among Black and Native American individuals, which happen to be the groups that have the highest incidence and

WASHINGTON — Among adults with eosinophilic esophagitis, weight gain while undergoing dietary therapy was associated with poor treatment response, regardless of baseline weight status, according to data presented at Digestive Disease Week. “EoE prevalence has increased alongside the obesity epidemic,” Stephanie A. Borinsky, MD, a gastroenterology fellow in the department of

CHICAGO — In patients with inflammatory bowel disease, a “strong and consistent three-way interaction” was identified between HLA-B27, male sex and the development of sacroiliitis, according to data presented at Digestive Disease Week.Sacroiliitis occurs in approximately 20% of patients with IBD, often aligned with male sex and HLA-B27 status; however, large-scale studies on the

CHICAGO — Colorectal cancer screening rates at federally qualified health centers were significantly higher in states that expanded Medicaid under the Affordable Care Act vs. states that did not, according to data at Digestive Disease Week. “Federally qualified health centers are a relatively new place for people to get primary care, since the Affordable Care Act started funding them

CHICAGO — Greater consumption of artificial sweeteners, specifically those that do not contain aspartame, resulted in “marked effects” on the duodenal microbiome profile, according to data presented at Digestive Disease Week. “As physicians, we see a number of patients who consume artificial sweeteners for a variety of reasons,” Ruchi Mathur, MD, director of clinical

When James Casey, acclaimed saxophonist for the Trey Anastasio Band, first began feeling the dull ache on the right side of his abdomen, it was easy enough to ignore — and colorectal cancer was the last thing he would have considered.“I didn’t know that something was wrong,” Casey said during this year’s Colorectal Cancer in Young Black Americans event, presented by