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Decoding tauopathies: New study identifies non-coding RNA as a key player in Alzheimer's

Researchers at Washington University School of Medicine identify a key step in the development of harmful tau tangles, offering a potential target for preventing brain damage in diseases like Alzheimer's. The study highlights the role of long noncoding RNAs, particularly SNHG8, in stress granule formation and tau aggregation, opening new avenues for treatment.
Danielle Ellis Celeste Karch Reshma Bhagat Washington University School Of Medicine Washington University School Stress Granule Formation

Decoded: How toxic proteins accumulate in Alzheimer's, Parkinson's?

Researchers, including one of Indian-origin, have identified how tau protein -- part of the brain's infrastructure -- gets knotted up into tangles and turns toxic in Alzheimer's, Parkinson's and other brain diseases.Under normal circumstances, ...
New York United States Celeste Karch Reshma Bhagat Washington University School Of Medicine Washington University School

How do toxic proteins accumulate in Alzheimer's and other diseases? - The Source - Washington University in St. Louis

Researchers at Washington University School of Medicine in St. Louis have identified a key step in the development of destructive tau tangles in the brain. The discovery could lead to new approaches to treating a group of neurodegenerative diseases known as tauopathies, such as Alzheimer’s and Parkinson’s.
Celeste Karch Reshma Bhagat Washington University School Of Medicine Washington University School
Source: wustl.edu

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