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SynNotch CAR circuits enhance solid tumor recognition and promote persistent antitumor activity in mouse models

Science for just $15 USD. Short circuiting solid tumors Two major hurdles in chimeric antigen receptor (CAR) T cell therapy for solid tumors are ensuring specificity to tumor cells without affecting healthy cells and avoiding tumor escape due to antigen loss. To address these challenges, Hyrenius-Wittsten et al. and Choe et al. developed synthetic Notch (synNotch)–CAR T cells targeting solid tumor antigens and used them to treat mouse models of mesothelioma, ovarian cancer, and glioblastoma...
United Kingdom Takara Bio Facsaria Iiiu Chan Zuckerberg Biohub Celltrace Violet B Ebert Addgene

Incucyte® SX5 Live-Cell Analysis System

Rating: Application Area:Live cell imaging and analysis "The Incucyte SX5 is an easy-to-use live-cell imaging technology, saving our scientists time in both experimental set-up and monitoring whilst providing exceptional, previously unobtainable readouts. Protocols for a wide range of lab-based assays are freely available and easy to follow. Many of our scientists have already switched many of their traditional lab-based assays to use the Incucyte technology instead. The ability to mo...
Cell Analysis System Incucyte Sx5 Live Cell Analysis System Sartorius Group செல் பகுப்பாய்வு அமைப்பு சர்த்தொறிூச் குழு

Incucyte® SX5 Live-Cell Analysis System

Rating: Application Area:Live cell imaging and analysis "The Incucyte SX5 is an easy-to-use live-cell imaging technology, saving our scientists time in both experimental set-up and monitoring whilst providing exceptional, previously unobtainable readouts. Protocols for a wide range of lab-based assays are freely available and easy to follow. Many of our scientists have already switched many of their traditional lab-based assays to use the Incucyte technology instead. The ability to mo...
Cell Analysis System செல் பகுப்பாய்வு அமைப்பு

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