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Frontiers | Emergence of Dengue 4 as Dominant Serotype During 2017 Outbreak in South India and Associated Cytokine Expression Profile

Dengue virus infection is prevalent in tropical and sub-tropical regions of the world, which is fatal if untreated symptomatically. Emergence of new genotype within serotypes led to enhanced severity. The objective of the study is to identify the molecular characteristics of the DENV circulated during 2017 outbreak in Tamil Nadu, India and, to investigate the role of inflammatory cytokines in different โ€˜serotypesโ€™ and in โ€˜dengue severityโ€™. A total of 135 suspected samples were tested for...
United States United Kingdom New Delhi Tamil Nadu Sri Lanka Republic Of

Breakthrough treatment could improve the immune system's ability to destroy cancer cells

Breakthrough treatment could improve the immune systems ability to destroy cancer cells New research has identified potential treatment that could improve the human immune systems ability to search out and destroy cancer cells within the body. Scientists have identified a way to restrict the activity of a group of cells which regulate the immune system, which in turn can unleash other immune cells to attack tumors in cancer patients. "A patients immune system is more than able to detect and rem...
United States Nullin Divecha Emily Henderson National Institute Of Molecular Genetics University Of Southampton Cell Signalling

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