Cell Syst News Today

In metazoan organisms, cell competition acts as a quality control mechanism to eliminate unfit cells in favour of their more robust neighbours1,2. This mechanism has the potential to be maladapted, promoting the selection of aggressive cancer cells3–6. Tumours are metabolically active and are populated by stroma cells7,8, but how environmental factors affect cancer cell competition remains largely unknown. Here we show that tumour-associated macrophages (TAMs) can be dietarily or genetical...

2Informatic Unit, INMEDIT SAS and Faculty of Engineering, University of Cartagena, Cartagena, Colombia 3Clinica Respiratoria y de Alergias, Cartagena, Colombia 4Departamento de Investigaciones, Fundación Cardioinfantil, Bogotá, Colombia 5Research Department - CINEUMO, Fundación Neumológica Colombiana, Bogotá, Colombia 6Research Department and Specialization Program in Pulmonology, Universidad de la Sabana, Bogotá, Colombia Background: Chronic obstructive pulmonary disease (COPD) is associ...