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We must do better to accommodate special needs children | News, Sports, Jobs

We call upon area civic, charitable and public leaders to evaluate how they accommodate special needs children and adults when holding events. The announcement this week โ€” featured on Page A1 in todayโ€™s edition โ€” that a new one-day Camp Cadet for special needs youth has opened our eyes. Alyssa Lacy is a special needs […]
Gerald Lacy Brinker Jr Alyssa Lacy Colleen Xetchakis Camp Cadet Charles Shoemaker

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New approach to tame botulinum toxin for drug delivery

New approach to tame botulinum toxin for drug delivery While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known. These toxins are often found in contaminated food (home canning being a major culprit). Infants can also develop botulism from ingesting C. botulinum spores in honey, soil, or dust; the bacterium then colonizes their intestines and produces the toxin. Once paralysis devel...
Tufts University United States Shin Ichiro Miyashita Emily Henderson Boston Children Hospital Department Of Urology Science Translational Medicine

Botulism breakthrough? Taming botulinum toxin to deliver therapeutics

ย E-Mail IMAGE:ย The toxin-based delivery platform consists of the modified botulinum toxin at upper left (protease domain in gold, translocation domain in blue, and receptor-binding domain in purple) and the nanobody (the... view moreย  Credit: Sicai Zhang/Dong Lab, Boston Childrens Hospital While rare, botulism can cause paralysis and is potentially fatal. It is caused by nerve-damaging toxins produced by Clostridium botulinum -- the most potent toxins known. These toxins are often fou...
Tufts University United States Jie Zhang Shin Ichiro Miyashita Sicai Zhang Boston Children Hospital Department Of Urology

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