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Supported Liquid Extraction versus Liquid-Liquid Extraction: Extracting Acidic, Basic and Neutral Analytes from Plasma

Mar 11 2021 Read 153 Times Author: James Edwards on behalf of Porvair Sciences Free to read Unlock Sample preparation is a key process when running any samples on a chromatography instrument. No matter how good the instrument is, to get the best sensitivity and reproducibility sample clean-up needs to be performed. A traditional method has been to use liquid-liquid extraction (LLE) which allows transfer of analyte from an aqueous solution to an organic solution. However, LLE...
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