A drug target for erectile dysfunction to help improve fertility, sexual activity, and wellbeing: mendelian randomisation study
Objective To investigate the association of genetically proxied (using a surrogate biomarker) inhibition of phosphodiesterase 5 (PDE5), an established drug target for erectile dysfunction, with fertility, sexual behaviour, and subjective wellbeing. Design Two sample cis-mendelian randomisation study. Setting Summary data on genetic associations obtained from the International Consortium for Blood Pressure and UK Biobank. Participants Individuals of European ancestry from the International Consor...
Source: bmj.com