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Impact and cost-effectiveness of the 6-month BPaLM regimen for rifampicin-resistant tuberculosis in Moldova: A mathematical modeling analysis

Author summary Why was this study done? Drug resistance poses a major barrier to the effective treatment of tuberculosis, especially in Moldova and other post-Soviet states which have the highest levels of resistance in the world. Individuals with tuberculosis resistant to the key drug rifampicin face a worse prognosis, a longer and more expensive course of treatment, and more side effects than individuals with rifampicin-susceptible tuberculosis. Until recently, the standard of care for rifam...
United States United Kingdom South Africa Jennifer Thorley National Institute Of Allergy Decision Science Methods Group At Erasmus University
Source: plos.org

Tafenoquine following G6PD screening versus primaquine for the treatment of vivax malaria in Brazil: A cost-effectiveness analysis using a transmission model

Author summary Why was this study done? Radical cure with primaquine or recently approved tafenoquine is required to clear the dormant liver parasites of vivax malaria. While single-dose tafenoquine overcomes the barrier of patient adherence to the current 7-day primaquine treatment, it costs more and requires screening for glucose-6-phosphate dehydrogenase (G6PD) deficiency. While the impact of changing policies to tafenoquine after G6PD screening on transmission has been evaluated, the assoc...
Papua New Guinea United States South Korea Republic Of Korea Monte Carlo Jamesg Beeson
Source: plos.org

Costs and cost-effectiveness of influenza illness and vaccination in low- and middle-income countries: A systematic review from 2012 to 2022

In a systematic review of economic evaluations, Gharpure and team examine the costs of influenza illness and vaccination programs in low- and middle-income countries to assess potential barriers to global implementation. Full length: In this systematic review of economic evaluations, Radhika Gharpure and colleagues examine the costs of influenza illness, the costs of influenza vaccination programs, and the cost-effectiveness of vaccination from low- and middle-income countries to assess whether ...
United States South Africa Britni Burkhardsmeier Chris Chadwick Joanna Taliano Rakhat Akmatova
Source: plos.org

Wider access to antivenom in Brazil's Amazon

<p>A study by scientists and physicians from Duke University and two Brazilian institutions evaluated the cost-effectiveness of making snake bite antivenom more available in the Amazonas region. Expanding access to antivenom at both hospitals and community health centers would produce the largest benefits, averting up to 3,922 disability-adjusted life-years (DALYs) while yielding economic benefits of up to US$8.98 million.The findings appear in the January 2024 issue of The Lancet Regional...
United States Thiago Rocha Hui Wen Charlesj Gerardo Emilyr Smith Armand Zimmerman

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Cost-effectiveness analysis of interventions to improve diagnosis and preventive therapy for paediatric tuberculosis in 9 sub-Saharan African countries: A modelling study

In a modelling study, Nyashadzaishe Mafirakureva and colleagues, examine the cost-effectiveness of health interventions designed to improve tuberculosis prevention and treatment in children.
United Kingdom Democratic Republic Of The Congo The Congo Lise Denoeud Monte Carlo Maryline Bonnet
Source: plos.org

New Study Demonstrates Ropeginterferon Alfa-2b-njft Is a Cost-Effective Treatment Option for a Broad Range of Patients with Polycythemia Vera

BURLINGTON, Mass., August 04, 2023--PharmaEssentia USA Corporation, a subsidiary of PharmaEssentia Corporation (TPEx:6446), a global biopharmaceutical innovator based in Taiwan leveraging deep expertise and proven scientific principles to deliver new biologics in hematology and oncology, today announced the publication of a cost-effectiveness analysis of ropeginterferon alfa-2b-njft (marketed as BESREMi®) in the Journal of Comparative Effectiveness Research. The analysis, titled "Cost-...
United States South Korea T Ai Pei Raymond Urbanski Pharmaessentia Tpex Aaron Gerds
Source: yahoo.com

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