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Neoadjuvant pembrolizumab achieves major pathologic response in more than half of patients with resectable melanoma

In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab.
United States Michaelc Lowe Kaiser Permanente Elizabethi Buchbinder Megan Othus G Paul Wright

Major pathologic response to neoadjuvant pemb

<p style="text-align:start">In exploratory analyses of results from the SWOG S1801 trial in patients with stage III-IV resectable melanoma, researchers saw a major pathologic response in more than half of surgical specimens taken from patients who had been treated with neoadjuvant (pre-operative) pembrolizumab. These and other results of the analyses are presented as a proffered paper (Abstract LBA48) at the European Society of Medical Oncology (ESMO) Congress 2023 in Ma...
United States Vernonk Sondak Michaelc Lowe Aparna Hegde Johnm Kirkwood Kaiser Permanente

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Why breakthrough COVID deaths can be misunderstood

IStock/koto_feja(NEW YORK) -- The death of former Secretary of State Colin Powell due to COVID-19 complications has sparked conversations about breakthrough deaths among vaccinated individuals. It would be inaccurate, however, to jump to any conclusions about vaccine effectiveness from a single breakthrough death such as Powell's, who was 84 years old, immunocompromised and being treated for multiple myeloma, a blood-borne cancer that "in and of itself can lead to compromised immunity,...
New York United States South Shore Dana Farber Cancer Institute Paul Richardson Craig Devoe

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