Page 36 - Crispr News Today

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled

When Jennifer Doudna was in sixth grade, she came home one day to find that her dad had left a paperback titled

CRISPR screen identifies clinically approved immunosuppressants that could treat coronavirus infections Researchers in Switzerland and Germany have identified host cell factors required for coronavirus replication that could serve as targets for treatment with clinically-approved drugs. The team found that several autophagy-related genes were common host defense factors required for the replication of both endemic and emerging coronaviruses. These coronaviruses include the novel severe acute re...

Immunologists map unknown biological machinery to produce memory T cells Immunologists at St. Jude Childrens Research Hospital have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses, and tumor cells. The findings have multiple implications for how the adaptive immune system responds to infections to generate such memory T cells. The experiments revealed mechanisms that inhibit the development of the long-lived memory T ce...

From left: Hongbo Chi, Ph.D., Hongling Huang, Ph.D., and PeiPei Zhou, Ph.D., all of St. Jude Immunology, have mapped the previously unknown biological...

Coming of Phage: Clinical trial underscores safety of technology battling E. coli triggered UTIs Locus Biosciences says the results of its early stage clinical trial for CRISPR-enhanced bacteriophage therapy shows its precision medicine asset is safe and well tolerated. Announcing the completion of its Phase 1b study of LBP-EC01, a CRISPR-Cas3-enhanced bacteriophage (crPhage) product targeting Escherichia coli (E. coli) ​bacteria that cause urinary tract infection...

New gene-editing tool enables programming of sequential cuts over time Researchers from the University of Illinois Chicago have discovered a new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time. CRISPR is a gene-editing tool that allows scientists to change the DNA sequences in cells and sometimes add a desired sequence or genes. CRISPR uses an enzyme called Cas9 that acts like scissors to make a cut precisely at a desired location in the DNA. O...

A new gene-editing technique that allows for the programming of sequential cuts -- or edits -- over time has been discovered.

The Globe and Mail Bookmark Please log in to listen to this story. Also available in French and Mandarin. Log In Create Free Account Getting audio file ... This translation has been automatically generated and has not been verified for accuracy. Full Disclaimer Penguin Random House Canada Kazuo Ishiguro was about a third of the way through writing his eighth novel when he was awarded the Nobel Prize. By the time he was working on edits to the manuscript, he was in lockdown amid a global ...