Page 38 - Crispr News Today

ERS Genomics and ZeClinics Sign CRISPR/Cas9 License Agreement ZeClinics is applying CRISPR technology to create gene edited zebrafish disease models ERS Genomics Limited, which was formed to provide broad access to the foundational CRISPR/Cas9 intellectual property co-owned by Dr. Emmanuelle Charpentier, and ZeClinics, a contract research organization using zebrafish to carry out services focused on analyzing the safety, efficacy and biomedical relevance of new compounds, today announced a non-...

Brain Development And The Neanderthal Mini-brain The complete genome  of the Neanderthal species was sequenced in 2013, from a phalanx (finger bone) Neanderthal fossil found in Siberia.  With this information in hand, the UC San Diego School of Medicine research team sought to isolate  Neanderthal genes  that were intimately involved in brain development processes. They eventually settled on NOVA1 as a candidate worth studying, and then set about designing an experiment that would prove ...

We propose five principles that could guide a proper ethical and legal framework for germline editing and similar technologies.

AbbVie and Caribou Biosciences have entered into a collaboration and license agreement for the research and development of chimeric antigen receptor (CAR)-T cell therapeutics.

Modified CRISPR/Cas9 complex targets specific histones Finding a needle in a haystack is hard enough. But try finding a specific molecule on the needle. Rice University researchers have achieved something of the sort with a new genome editing tool that targets the supporting players in a cells nucleus that package DNA and aid gene expression. Their work opens the door to new therapies for cancer and other diseases. Rice bioengineer Isaac Hilton, postdoctoral researcher and lead author Jing Li a...

Chinese scientists have successfully prolonged the lives of mice by using CRISPR.

New study by the IBMCP of the UPV university facilitates the use of the CRISPR genomic editing technique on plants.

Study implicates disruption in prenatal neurogenesis in the development of ASDs A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs). The study also shows that estrogen, perhaps in a form produced within brain cells, can protect against this disruption and steer the brain on a normal co...

Tissue stem cells can self-renew and differentiate, supplying cells necessary for tissues at various developmental stages. However, detailed analysis in...

Date Time CRISPR improves method for studying gene functions Since the genetics revolution, biologists have been working to understand the roles that individual genes play, often with the help of advanced techniques. One such method, mosaic analysis, has led to many discoveries of the functions of genes. Although mosaic analysis has been widely used in Drosophila, a popular model organism, it is much harder to implement in other organisms. A new paper describes a technique called Mosaic Analysi...