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Progeria study finds base-editing therapy lengthens lifespan in mice

Luke Koblan sat at his desk, staring at some data. Excited but baffled, the grad student thought, there’s no way those numbers could be right. He shared the results with his boss, Professor David Liu, and today, that data has spurred a team of scientists from the Broad Institute of MIT and Harvard (including Koblan and Liu), the National Institutes of Health, and Vanderbilt University Medical Center to achieve an almost unbelievable leap for the CRISPR gene-editing tool known as base editing,...
Leslie Gordon Jonathan Brown Charles Lin Michael Erdos Brown University Dana Farber Cancer Institute

CRISPR Technology Now Tracks When Cancer Would Spread in the Body!

(Photo : Pixabay) In a study published recently in Science publication last January 21, the researchers coming from different backgrounds have devised a way using the CRISPR Tool, to track cells using the genetic engineering of a person and their cells. This method would now look deep into the basis of a genetic strand and see the cells that are healthy and affected by cancer to see its growth.  Cancer cells are often confined to a certain area it chooses and remains there to infect the cell...
Jonathan Weismann Michelle Chan Weismann Lab Genetic Engineering Tracking Cancer Was Originally Intended

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform A team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce vaccines. They used severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) as a model to develop the platform. The study is currently available on the Design of T4-SARS-CoV-2 nanovaccine by CRISPR engineering. Engineered DNA...
United States Sanchari Sinha Dutta Supplementary Video While Soc Design Multiplex Nano Technology

Gene-cutting system may play second role as a genetic dimmer switch

Gene-cutting system may play second role as a genetic dimmer switch In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a genetic dimmer switch for CRISPR-Cas9 genes. Its role of dialing down or dimming CRISPR-Cas9 activity may help scientists develop new ways to genetically engineer cells for research purposes. A summary of the findings was published Jan....
United States Johns Hopkins Joshua Modell Emily Henderson Emory University Johns Hopkins University School Of Medicine

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Research Week Features Hot Topics and New Tools

Research Week is January 25-29 The plans have been adjusted a bit for virtual participation, but all systems are go for Research Week 2021 at Duke, Jan. 25-29. This first-ever event will include the inaugural Ingrid Daubechies Lecture and updates from Duke researchers working on the frontiers of political science, Covid, Quantum computing, CRISPR gene editing and artificial intelligence. Participants can earn some Responsible Conduct of Research tra...
Gigliola Staffilani Research Larry Carin Office Of Research Duke Research Week Research Week Research Town Hall

CRISPR gene-editing urgently needs an off-switch – now we have one

CRISPR gene-editing urgently needs an off-switch – now we have one Making changes to genes with CRISPR has the potential to cure diseases and feed the world, if we can learn to control it. Now it looks like viruses hold the solution Technology 13 January 2021 Pete Reynolds THERE is a technology that could tackle some of life’s most pressing problems, from disease to malnutrition. It could fix medical conditi...
Pete Reynolds Gege Li Scientist Default Image Gene Editing Genetic Modification பீட் ரெனால்ட்ஸ்

First steps toward uncovering CRISPR/Cas gene doping in plasma

First steps toward uncovering CRISPR/Cas gene doping in plasma All athletes want to be at the top of their game when they compete, but some resort to nefarious approaches to achieve peak muscle growth, speed and agility. Recent developments in gene editing technology could tempt athletes to change their DNA to get an edge. Now, researchers reporting in ACS Analytical Chemistry demonstrate first steps toward detecting this type of doping both in human plasma and in live mice. The gene editing m...
Mario Thevis Emily Henderson Analytical Chemistry World Anti Doping Agency எமிலி ஹென்டர்சன் பகுப்பாய்வு வேதியியல்

COMMENTARY: The silver linings (yes, there were some) of 2020

FOR OBVIOUS reasons, 2020 will not go down as a good year. At the same time, it has brought more scientific progress than any year in recent memory—and these advances will last long after COVID-19 as a major threat is gone. Two of the most obvious and tangible signs of progress are the mRNA vaccines now being distributed across America and around the world. These vaccines appear to have very high levels of efficacy and safety, and they can be produced more quickly than more conventional va...
United States Tyler Cowen Covid 19 Silver Lining Mrna Vaccines Vaccine Technology

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