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Background: People with Ehlers-Danlos Syndromes and Hypermobility Spectrum Disorders are hampered in their social participation, especially in the social relationships they have. Objective: The aim of this study is to research the impact of hypermobile Ehlers-Danlos Syndrome (hEDS) and Hypermobile Spectrum Disorders (HSD) on interpersonal interactions and relationships. Methods: A phenomenological hermeneutic study was performed. Semi-structured interviews were used to explore the experiences of...

The emplacement of the Siberian Traps, the Central Atlantic Magmatic Province (CAMP) and the Wrangellia have been linked to end-Permian, end-Triassic mass extinctions, and to the Carnian Pluvial Episode (CPE), respectively. Exploring the timing, eruptive styles, and volatile degassing of these Large Igneous Provinces (LIPs) is crucial to understand their causal link to the catastrophic environmental crises that punctuated the Triassic. In this study we review the main characteristics of these LI...

Dust particle studies in ice cores from the tropical Andes provide important information about climate dynamics. We investigated dust concentrations from a 22.7 m ice-core recovered from the Quelccaya Ice Cap (QIC) in 2018, representing 14 years of snow accumulation. The dust seasonality signal was still preserved with homogenization of the record due to surface melting and percolation. Using a microparticle counter, we measured the dust concentration from 2–60 μm and divided the annual dust ...

Glacier inventory is the basic data for hydrological, water resources and climate change research. Glacier inventories have been created for the Third Pole Region (TPR) or high Asia, yet they are different in coverage area and vary largely in quality. It is thus necessary to assess their quality in order to provide information for potential users to choose the right glacier inventories. Using the analytic hierarchy process, this study selects eight assessment factors and assesses the comprehensi...

The effects of the climate change including an increase in the average global temperatures, and abnormal weather events such as frequent and severe heatwaves are emerging as a worldwide ecological concern due to their impacts on plant vegetation and crop productivity. In this review, the molecular processes of plants in response to heat stress—from the sensing of heat stress, the subsequent molecular cascades associated with the activation of heat shock factors and their primary targets (heat ...

Many flowers are fed on by florivores, but we know little about if and how feeding on flowers affects their visual and chemical advertisement and nectar resource, which could disrupt pollination. Here, we investigated if damages caused by florivores compromise a Neotropical hummingbird-pollination system, by modifying the floral advertisements and the nectar resource. We surveyed natural florivory levels and patterns, examined short-term local effects of floral damages caused by the most common ...

Stroke is one of the leading causes of death among adults worldwide. The World Health Organization (WHO) officially declared a COVID-19 pandemic on March 11, 2020.The first case in Mexico was confirmed on February 28, 2020, subsequently becoming one of the countries most affected by the pandemic. In this paper, we aim to describe changes in the demand for stroke healthcare assistance at the National Institute of Neurology and Neurosurgery during the pandemic. For this study, we analyzed data for...

Autoimmune toxicities, while common following treatment with cancer immunotherapies, are not well-characterized in patients treated with BRAF/MEK inhibitors. Emerging data suggest that autoimmune effects may be linked with superior responses to both treatment modalities; however, there is little evidence describing mechanisms of immune-related toxicity for patients on BRAF/MEK inhibitors. Here we describe the experience of a 59-year-old HLA-A2, A29, B27-positive male patient with recurrent/metas...

Food security and livelihoods among smallholder farmers in sub-Saharan Africa are often constrained by limited farm resource endowment. It can be difficult to improve resource endowment given barriers such as low land availability and the unaffordability of agricultural inputs, so here we ask whether farmers can gain a better return on their resources through optimising their farm strategy in terms of the composition and/or diversity of crop and livestock species raised. Our survey of 1133 small...

During the COVID-19 pandemic, medical products have been crucial to the global fight against the disease. As a major manufacturing country, China occupies an important position in the medical products field. However, China's terms of trade are not commensurate with its status as a major exporter of medical products. Therefore, studying China's market power in medical product exports has important practical significance for determining China's value chain position in the global market...