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Frontiers | Higher Adherence to the Mediterranean Diet Is Associated With Preserved White Matter Integrity and Altered Structural Connectivity

The Mediterranean diet (MedDiet) has been associated with cognitive performance. Yet, controlled trials have yielded contradictory results. To tackle this controversy, a comprehensive multimodal analysis of the association of the MedDiet with cognitive performance and brain structure in normative aging is still necessary. To address this issue, community-dwellers ≥50 years from a cohort study on normative aging (n=76) underwent a i) magnetic resonance imaging session with two acquisitions: str...
United States United Kingdom Eteläuomen Läi Martin Moreno Castilla La Manacha City Of

Frontiers | COVID-19 in Saudi Arabia: An Overview

Background: Saudi Arabia, a prominent Arabian country, has 35.3 million persons living in 2.2 million square kilometers, undergone serious threats, recently, due to the COVID-19 pandemic. With the built in infrastructure and disciplined life, the country could address this pandemic. Aims: This analysis of COVID-19 cases in Saudi Arabia, attempts to assess the situation, explore its global percentage share, percentage of population affected, and local distribution from the beginning of infection ...
Saudi Arabia King Saud University Ar Riya Al Madinah United States United Arab Emirates

Frontiers | Nested Climate Accounting for Our Atmospheric Commons—Digital Technologies for Trusted Interoperability Across Fragmented Systems

The Paris Agreement’s decentralized and bottom-up approach to climate action poses an enormous accounting challenge by substantially increasing the number of heterogeneous national, sub-national, and non-state actors. Current legacy climate accounting systems and mechanisms are insufficient to avoid information asymmetry and double-counting due to actor heterogeneity and fragmentation. This paper presents a nested climate accounting architecture that integrates several innovative digital techn...
New York United States France General United Kingdom T Ai Pei The Commons

Frontiers | Numerous Sublinear Sets of Holes in Sediment on the Northern Mid-Atlantic Ridge Point to Knowledge Gaps in Understanding Mid-Ocean Ridge Ecosystems

On 13 July 2004, during an expedition exploring biodiversity along the northern Mid-Atlantic Ridge, an ROV dive recorded videos of numerous sublinear sets of holes in sediment at ca. 2082 m depth. The location was north of the Azores. Each set appeared track-like. Lengths of individual series ranged from <1 m to many meters. Each was straight or gently curved. Some series intersected or crossed. Close examination of the holes showed them to be elongate, with the long axis parallel to the axis...
New York United States Romania General Ad Mcintyre Hoboken Atlantic Ridge Jb Hersey Baltimore

Frontiers | Aspirin Repurposing in Folate-Decorated Nanoparticles: Another Way to Target Breast Cancer

Breast cancer affects more than one million women per year worldwide. Through this study, we develop a nanoparticle-based drug delivery system to target breast cancer cells. Aspirin has been found to inhibit thromboembolic diseases with its tumor-preventing activity. As a consequence, it relieves disease symptoms and severity. Here, mesoporous Silica Nanoparticles (MNP) have been used to deliver Aspirin to the tumor location. MNP-based Aspirin in folic acid (F)-conjugated Polydopamine (MNP-Asp-P...
United States United Kingdom Biochem Biophys Santa Clara Acta Bba Noncovalent Functionalization

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Frontiers | Geochemically Defined Space-for-Time Transects Successfully Capture Microbial Dynamics Along Lacustrine Chronosequences in a Polar Desert

The space-for-time substitution approach provides a valuable empirical assessment to infer temporal effects of disturbance from spatial gradients. Applied to predict the response of different ecosystems under current climate change scenarios, it remains poorly tested in microbial ecology studies, partly due to the trophic complexity of the ecosystems studied. The McMurdo Dry Valleys of Antarctica represent a trophically simple polar desert projected to experience drastic changes in water availab...
United States New York New Zealand Taylor Valley United Kingdom States Lee

Frontiers | Genome-Wide Association Analysis Reveals Genetic Loci and Candidate Genes for Chest, Abdominal, and Waist Circumferences in Two Duroc Pig Populations

Chest circumference (CC), abdominal circumference (AC), and waist circumference (WC) are regarded as important indicators for improving economic traits because they can reflect the growth and physiological status in pigs. However, the genetic architecture of CC, AC, and WC is still elusive. Here, we performed single-trait and multi-trait genome-wide association studies (GWASs) for CC, AC, and WC in 2206 American origin Duroc (AOD) and 2082 Canadian origin Duroc (COD) pigs. As a result, one novel...
Baden Wüberg United States New York Nat Genet Coheni Pearson J Clin Nutr

Frontiers | E-Learning Adoption in Higher Education Institutions During the COVID-19 Pandemic: A Multigroup Analysis

Using the DeLone and McLean (D&M) Model, the study explains the differences between female and male students’ accessibility to E-learning portals. This study compares female and male student groups regarding the usage of the E-learning portal in the higher education context. Using an online google survey, the data were collected from 254 students, including males and females. The study utilized PLS-SEM to perform a multi-group analysis examining female and male student groups. The multi-g...
New York United States Minas Gerais Republic Of South Africa North West Frontier

Frontiers | Molecular Docking and Dynamics Studies to Explore Effective Inhibitory Peptides Against the Spike Receptor Binding Domain of SARS-CoV-2

The spread of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has become a pandemic due to the high transmission and mortality rate of this virus. The world health and economic sectors have been severely affected by this deadly virus, exacerbated by the lack of sufficient efficient vaccines. The design of effective drug candidates and their rapid development is necessary to combat this virus. In this study, we selected 23 antimicrobial peptides from the literature and predicted thei...
Saudi Arabia United States San Diego J Neuroimmune Pharmacol Albiol Matanic Dermatophagoides Pteronyssinus

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