Cryptococcus Neoformans News Today

Cryptococcal meningitis is a fungal infection affecting the coverings of the brain (meninges). It is rare in healthy persons and affects those with poor immunity such as AIDS patients or on immunosuppressive treatments.

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Cryptococcal meningitis is a fungal infection affecting the coverings of the brain (meninges). It is rare in healthy persons and affects those with poor immunity such as AIDS patients or on immunosuppressive treatments.

Fungal infections have become an increasing threat as a result of growing numbers of susceptible hosts and diminishing effectiveness of antifungal drugs due to multi-drug resistance. This reality underscores the need to develop novel drugs with unique mechanisms of action. We recently identified 5-(N,N-hexamethylene)amiloride (HMA), an inhibitor of human Na+/H+ exchanger isoform 1, as a promising scaffold for antifungal drug development. In this work, we carried out susceptibility testing of 45 ...

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Scientists found out that the deadly fungus is known to cause meningitis can 'shapeshift' into the necessary structure so that it can enter the human brain.

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A new study by researchers from the University of Utah Health has found that C. neoformans cells transform into smaller cells that develop the capacity to travel to the brain and infect it

The mechanism by which the fungus Cryptococcus neoformans is resilient to fungus-specific medications has been uncovered by an international research team.