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Lessons from applied large-scale pooling of 133,816 SARS-CoV-2 RT-PCR tests

Batch testing for SARS-CoV-2 Frequent and accurate RT-PCR–based testing is essential for preventing and managing SARS-CoV-2 infection; however, active infection surveillance is still often limited by time or resources. Cleary et al. demonstrate that considering population-level viral prevalence and individual viral loads allows for efficiency gains upon pooled testing with minimal loss of sensitivity, both theoretically and as validated in vitro using human swab and sputum samples. Barak et...
Hebrew University Israel General Ha Afon Yutti Daitch Irit Fogel Gil Benedek

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