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Orchestra BioMed Announces Presentation of Positive Long-Term Clinical Results from MODERATO II Control Patients Crossover Extension Study of BackBeat CNT at TCT 2022

Statistically significant mean reductions of 10.3 mmHg in 24-hour ambulatory systolic blood pressure and 11.7 mmHg in ambulatory pulse pressure after 6 months of therapy in control patients who crossed over to BackBeat CNT following completion of the randomized portion of the MODERATO II study
United States Daniel Burkhoff Circulatory Support Research At Cardiovascular Foundation Orchestra Biomed Inc Orchestra Biomed Patients Crossover Extension Study

Hints of Benefit With Levosimendan in Pulmonary Hypertension Due to HFpEF

April 15, 2021 For patients who have pulmonary hypertension and heart failure with preserved ejection fraction (PH-HFpEF), treatment with levosimendan (Simdax; Tenax Therapeutics) can improve both pulmonary congestion and submaximal exercise capacity when compared with placebo, according to the results of a small study. While the phase II study missed its primary endpoint, which was a reduction in pulmonary capillary wedge pressure (PCWP) during exercise, levosimendan did reduce PCWPs across t...
New York United States Daniel Burkhoff Journal Of The American College Cardiology World Health Organization Drug Administration
Source: tctmd.com

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