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KTVU KTVU Mornings On 2 At 7am April 14, 2016

To the sierra. Here is new video from interstate 80 this morning. If you plan to drive up, bring your chains. Right now chains are required on parts of interstate 80. The snow is welcome news for a lot of ski resorts. They are expecting have their final runs this weekend. However, mt. Rose near reno they announced they are extending operations through may. High surf advisory is in effect at bay area beaches today. Some spots could see waves as high as 6 feet. Officials remind us during the advis...
Redwood City United States Central Valley New York Santa Clara County San Francisco Park

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Understanding Topotecan's Cancer Inhibiting Power

Topotecan, a cancer inhibitor, interacts with an important protein (TopoIB), causing a (cancer) cell to malfunction. The TopoIB protein is responsible for the removal of loops from DNA, which arise amongst other things during cell division. The TopoIB protein binds to the DNA molecule, clamps around it and cuts one of the two DNA strands, after which it allows it to unwind and finally joins the broken ends together. Until now it has been supposed that topotecan only causes the TopoIB protein ...
Nynke Dekker Komaraiah Palle Daniel Koster Daniela Koster Jude Children Research Hospital Memphis United States University Of Delft

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